Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV receptor.

Bibliographic Details
Main Authors: Mayank Srivastava, Ying Zhang, Jian Chen, Devika Sirohi, Andrew Miller, Yang Zhang, Zhilu Chen, Haojie Lu, Jianqing Xu, Richard J. Kuhn, W. Andy Tao
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17638-y

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