Chemotherapy Effectiveness and Prognosis of Gastric Cancer Influenced by PTPN11 Polymorphisms

Chemotherapy Effectiveness and Prognosis of Gastric Cancer Influenced by PTPN11 Polymorphisms

Objective: Since gastric cancer (GC) cells exhibited higher grades of SHP-2 encoded by PTPN11 than normal cells, it would be intriguing to explore whether PTPN11 single nucleotide polymorphisms (SNPs) would influence chemotherapy effectiveness and GC prognosis among a Chinese population. Methods: Al...

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Bibliographic Details
Main Authors: Chuanjun Zhuo, Mingjing Shao, Ce Chen, Chongguang Lin, Deguo Jiang, Guangdong Chen, Hongjun Tian, Lina Wang, Jie Li, Xiaodong Lin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Gastric cancer
PTPN11
SNP
Chemotherapy
Prognosis
Gene-environment interaction
Online Access:http://www.karger.com/Article/FullText/447856

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