Alterations of Dermal Connective Tissue Collagen in Diabetes: Molecular Basis of Aged-Appearing Skin.

Alterations of the collagen, the major structural protein in skin, contribute significantly to human skin connective tissue aging. As aged-appearing skin is more common in diabetes, here we investigated the molecular basis of aged-appearing skin in diabetes. Among all known human matrix metalloprote...

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Bibliographic Details
Main Authors: Angela J Argyropoulos, Patrick Robichaud, Rebecca Mutesi Balimunkwe, Gary J Fisher, Craig Hammerberg, Yan Yan, Taihao Quan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4841569?pdf=render