Prevention of vaginal SHIV transmission in macaques by a coitally-dependent Truvada regimen.

BACKGROUND: Daily pre-exposure prophylaxis (PrEP) with Truvada (a combination of emtricitabine (FTC) and tenofovir (TFV) disoproxil fumarate (TDF)) is a novel HIV prevention strategy recently found to prevent HIV transmission in men who have sex with men and heterosexual couples. We previously showe...

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Bibliographic Details
Main Authors: Jessica Radzio, Wutyi Aung, Angela Holder, Amy Martin, Elizabeth Sweeney, James Mitchell, Shanon Bachman, Chou-Pong Pau, Walid Heneine, J Gerardo García-Lerma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3514231?pdf=render