Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula.

Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula.

The infection caused by Trichomonas vaginalis is the most common but overlooked non-viral sexually transmitted disease worldwide. Treatment relies on one class of drugs, the 5-nitroimidazoles, but resistance is widespread. New drugs are urgently needed. We reported the effect of crude and purified s...

Full description

Bibliographic Details
Main Authors: Patrícia de Brum Vieira, Nícolas Luiz Feijó Silva, Camila Braz Menezes, Márcia Vanusa da Silva, Denise Brentan Silva, Norberto Peporine Lopes, Alexandre José Macedo, Jaume Bastida, Tiana Tasca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5708768?pdf=render

Internet

http://europepmc.org/articles/PMC5708768?pdf=render

Similar Items