Abiraterone induces SLCO1B3 expression in prostate cancer via microRNA-579-3p

Abiraterone induces SLCO1B3 expression in prostate cancer via microRNA-579-3p

Abstract Understanding mechanisms of resistance to abiraterone, one of the primary drugs approved for the treatment of castration resistant prostate cancer, remains a priority. The organic anion polypeptide 1B3 (OATP1B3, encoded by SLCO1B3) transporter has been shown to transport androgens into pros...

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Bibliographic Details
Main Authors: Roberto H. Barbier, Edel M. McCrea, Kristi Y. Lee, Jonathan D. Strope, Emily N. Risdon, Douglas K. Price, Cindy H. Chau, William D. Figg
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90143-4

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