Δ9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression

Δ9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression

Acute Respiratory Distress Syndrome (ARDS) causes up to 40% mortality in humans and is difficult to treat. ARDS is also one of the major triggers of mortality associated with coronavirus-induced disease (COVID-19). We used a mouse model of ARDS induced by Staphylococcal enterotoxin B (SEB), which tr...

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Bibliographic Details
Main Authors: Amira Mohammed, Hasan F. K. Alghetaa, Kathryn Miranda, Kiesha Wilson, Narendra P. Singh, Guoshuai Cai, Nagireddy Putluri, Prakash Nagarkatti, Mitzi Nagarkatti
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
acute respiratory distress syndrome
Δ9-tetrahydrocannabinol
staphylococcal enterotoxin B
cytokine storm
apoptosis
Online Access:https://www.mdpi.com/1422-0067/21/17/6244

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