Antioxidant effect of endothelin-1 receptor antagonist protects the rat kidney against chronic injury induced by hypertension and hyperglycemia

Antioxidant effect of endothelin-1 receptor antagonist protects the rat kidney against chronic injury induced by hypertension and hyperglycemia

ABSTRACT Hypertension and Diabetes mellitus are the two main causes of chronic kidney disease that culminate in the final stage of kidney disease. Since these two risk factors are common and can overlap, new approaches to prevent or treat them are needed. Macitentan (MAC) is a new non-selective anta...

Full description

Bibliographic Details
Main Authors: Agnaldo Caires, Marcia Bastos Convento, Bianca Castino, Ala Moana Leme, Edson de Andrade Pessoa, Alef Aragão, Nestor Schor, Fernanda Teixeira Borges
Format: Article
Language:English
Published: Sociedade Brasileira de Nefrologia
Series:Brazilian Journal of Nephrology
Subjects:
Rats
Renal Insufficiency, Chronic
Endothelin-1
Antioxidants
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002019005027101&lng=en&tlng=en

Similar Items

Similar Items