Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer

Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer

Forkhead box transcription factor M1 (FOXM1) is a proliferation‐associated transcription factor involved in tumorigenesis through transcriptional regulation of its target genes in various cells, including dendritic cells (DCs). Although previous work has shown that FOXM1 enhances DC maturation in re...

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Bibliographic Details
Main Authors: Zhongshi Zhou, Hongdan Chen, Rui Xie, Hongjie Wang, Senlin Li, Qianqian Xu, Na Xu, Qi Cheng, Ying Qian, Rongrong Huang, Zekun Shao, Ming Xiang
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Molecular Oncology
Subjects:
colon cancer
dendritic cell
epigenetic modification
FOXM1
H3K79me2
pancreatic cancer
Online Access:https://doi.org/10.1002/1878-0261.12443

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