The interaction of endothelin-1 and TGF-β1 mediates vascular cell remodeling.

The interaction of endothelin-1 and TGF-β1 mediates vascular cell remodeling.

BACKGROUND: Pulmonary arterial hypertension is characterized by increased thickness of pulmonary vessel walls due to both increased proliferation of pulmonary arterial smooth muscle cell (PASMC) and deposition of extracellular matrix. In patients suffering from pulmonary arterial hypertension, endot...

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Bibliographic Details
Main Authors: Christopher Lambers, Michael Roth, Jun Zhong, Christoph Campregher, Petra Binder, Bernhard Burian, Ventzislav Petkov, Lutz-Henning Block
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3756002?pdf=render

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http://europepmc.org/articles/PMC3756002?pdf=render

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