Use of peptide nucleic acids to manipulate gene expression in the malaria parasite Plasmodium falciparum.

One of the major concerns in treating malaria by conventional small drug molecules is the rapid emergence of drug resistance. Specific silencing of essential genes by antisense oliogomers has been proposed as an alternative approach that may result in antimalarial activity which is not associated wi...

Full description

Bibliographic Details
Main Authors: Netanel Kolevzon, Abed Nasereddin, Shankar Naik, Eylon Yavin, Ron Dzikowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899306?pdf=render