The Modulatory Roles of N-glycans in T-Cell-Mediated Autoimmune Diseases

The Modulatory Roles of N-glycans in T-Cell-Mediated Autoimmune Diseases

Glycosylation is a ubiquitous posttranslational modification of proteins that occurs in the endoplasmic reticulum/Golgi. N-glycans and mucin-type O-glycans are achieved via a series of glycohydrolase- and glycosyltransferase-mediated reactions. Glycosylation modulates immune responses by regulating...

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Bibliographic Details
Main Authors: Ming-Wei Chien, Shin-Huei Fu, Chao-Yuan Hsu, Yu-Wen Liu, Huey-Kang Sytwu
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
N-glycan
O-glycan
autoimmune disease
multiple sclerosis
inflammatory bowel disease systemic lupus erythematosus
type 1 diabetes mellitus
Online Access:http://www.mdpi.com/1422-0067/19/3/780

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