Influence of primaquine and ritonavir interaction on CYP3A4 mRNA expression in HepG2 cell culture
<p><strong>Background:</strong> Concomitant treatment with antimalaria and antiretroviral drug is a new challenge in the management of malaria and HIV co-infection. Primaquine is a substrate and also an inhibitor of CYP3A4, while ritonavir is a substrate, an inhibitor, and also an...
Main Authors: | Adam Iskandarmudasyah, Melva Louisa, Arleni Arleni, Sri W.A. Jusman, Franciscus D. Suyatna |
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Format: | Article |
Language: | English |
Published: |
Faculty of Medicine Universitas Indonesia
2012-02-01
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Series: | Medical Journal of Indonesia |
Online Access: | http://mji.ui.ac.id/journal/index.php/mji/article/view/471 |
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