THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes toge...
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Sankt-Peterburg : NIIÈM imeni Pastera
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doaj-e02e836648ec4decbd62f3551e490a5e2021-09-21T14:01:25ZrusSankt-Peterburg : NIIÈM imeni PasteraInfekciâ i Immunitet2220-76192313-73982014-07-013327527810.15789/2220-7619-2013-3-275-278175THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSISO. V. Logvinenko0C. L. Rakitinа1D. G. Ponomarenko2M. V. Kostychenko3N. S. Sarkisian4T. V. Berdnikova5The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolAbstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.https://www.iimmun.ru/iimm/article/view/175brucellosislymphocyte subpopulationphagocytosisimmunoglobulinsnatural resistance |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
O. V. Logvinenko C. L. Rakitinа D. G. Ponomarenko M. V. Kostychenko N. S. Sarkisian T. V. Berdnikova |
spellingShingle |
O. V. Logvinenko C. L. Rakitinа D. G. Ponomarenko M. V. Kostychenko N. S. Sarkisian T. V. Berdnikova THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS Infekciâ i Immunitet brucellosis lymphocyte subpopulation phagocytosis immunoglobulins natural resistance |
author_facet |
O. V. Logvinenko C. L. Rakitinа D. G. Ponomarenko M. V. Kostychenko N. S. Sarkisian T. V. Berdnikova |
author_sort |
O. V. Logvinenko |
title |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_short |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_full |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_fullStr |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_full_unstemmed |
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS |
title_sort |
features of blood immunological parameters in patients with various forms of brucellosis |
publisher |
Sankt-Peterburg : NIIÈM imeni Pastera |
series |
Infekciâ i Immunitet |
issn |
2220-7619 2313-7398 |
publishDate |
2014-07-01 |
description |
Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy. |
topic |
brucellosis lymphocyte subpopulation phagocytosis immunoglobulins natural resistance |
url |
https://www.iimmun.ru/iimm/article/view/175 |
work_keys_str_mv |
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