THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS

Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes toge...

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Main Authors: O. V. Logvinenko, C. L. Rakitinа, D. G. Ponomarenko, M. V. Kostychenko, N. S. Sarkisian, T. V. Berdnikova
Format: Article
Language:Russian
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2014-07-01
Series:Infekciâ i Immunitet
Subjects:
Online Access:https://www.iimmun.ru/iimm/article/view/175
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spelling doaj-e02e836648ec4decbd62f3551e490a5e2021-09-21T14:01:25ZrusSankt-Peterburg : NIIÈM imeni PasteraInfekciâ i Immunitet2220-76192313-73982014-07-013327527810.15789/2220-7619-2013-3-275-278175THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSISO. V. Logvinenko0C. L. Rakitinа1D. G. Ponomarenko2M. V. Kostychenko3N. S. Sarkisian4T. V. Berdnikova5The Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolThe Federal Government Public Health Institution Stavropol Institute for Plague Control of the Rospotrebnadzor, StavropolAbstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.https://www.iimmun.ru/iimm/article/view/175brucellosislymphocyte subpopulationphagocytosisimmunoglobulinsnatural resistance
collection DOAJ
language Russian
format Article
sources DOAJ
author O. V. Logvinenko
C. L. Rakitinа
D. G. Ponomarenko
M. V. Kostychenko
N. S. Sarkisian
T. V. Berdnikova
spellingShingle O. V. Logvinenko
C. L. Rakitinа
D. G. Ponomarenko
M. V. Kostychenko
N. S. Sarkisian
T. V. Berdnikova
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
Infekciâ i Immunitet
brucellosis
lymphocyte subpopulation
phagocytosis
immunoglobulins
natural resistance
author_facet O. V. Logvinenko
C. L. Rakitinа
D. G. Ponomarenko
M. V. Kostychenko
N. S. Sarkisian
T. V. Berdnikova
author_sort O. V. Logvinenko
title THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_short THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_full THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_fullStr THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_full_unstemmed THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
title_sort features of blood immunological parameters in patients with various forms of brucellosis
publisher Sankt-Peterburg : NIIÈM imeni Pastera
series Infekciâ i Immunitet
issn 2220-7619
2313-7398
publishDate 2014-07-01
description Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.
topic brucellosis
lymphocyte subpopulation
phagocytosis
immunoglobulins
natural resistance
url https://www.iimmun.ru/iimm/article/view/175
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