THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS

THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS

Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes toge...

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Bibliographic Details
Main Authors: O. V. Logvinenko, C. L. Rakitinа, D. G. Ponomarenko, M. V. Kostychenko, N. S. Sarkisian, T. V. Berdnikova
Format: Article
Language:Russian
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2014-07-01
Series:Infekciâ i Immunitet
Subjects:
brucellosis
lymphocyte subpopulation
phagocytosis
immunoglobulins
natural resistance
Online Access:https://www.iimmun.ru/iimm/article/view/175
Description
Summary:Abstract. Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood. In patients with chronic form of disease the decline of T-helper and cytotoxic T-lymphocytes together with activation of humoral immunity and increasing of B-lymphocytes and levels of immunoglobulins A and G have been observed. Thus, revealed changes indicating the formation of secondary immunodeficiency in chronic disease course. Results of the study confirmed the needs for a permanent immunological monitoring of patients with brucellosis as well as conducting a comprehensive immunological testing of patients to develop the individual scheme of corrective therapy.
ISSN:2220-7619
2313-7398

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