Berberine induces apoptosis via ROS generation in PANC-1 and MIA-PaCa2 pancreatic cell lines

Pancreatic cancer is the fourth leading cause of cancer death. Gemcitabine is widely used as a chemotherapeutic agent for the treatment of pancreatic cancer, but the prognosis is still poor. Berberine, an isoquinoline alkaloid extracted fro...

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Bibliographic Details
Main Authors: S.H. Park, J.H. Sung, E.J. Kim, N. Chung
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000200111&lng=en&tlng=en