SUBSTITUTED 1,3-PHENYL(PYRIDYL) PROPENONES AND DERIVATIVES WITH THIOSEMICARBAZIDIC GROUPS. STRUCTRURE – (HL-60) ANTILEUKEMIA ACTIVITY RELATIONSHIP

SUBSTITUTED 1,3-PHENYL(PYRIDYL) PROPENONES AND DERIVATIVES WITH THIOSEMICARBAZIDIC GROUPS. STRUCTRURE – (HL-60) ANTILEUKEMIA ACTIVITY RELATIONSHIP

3-(4-(Dimethylamino)phenyl-1-(4-isothiocyanatophenyl)prop-2-en-1-one was obtained from the corresponding N,N-dimethylthyoureas by elimination of dimethylamine at heating with gaseous hydrogen chloride in chloroform and 1-(4-isothiocyanatophenyl)-3-(pyridin-2-il)prop-2-en-1-one by treating 1,1-dimeth...

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Bibliographic Details
Main Authors: Ana Popusoi, Nicanor Barba, Aurelian Gulea, Jenny Roy, Donald Poirier
Format: Article
Language:English
Published: Academy of Sciences of Moldova, Institute of Chemistry 2014-12-01
Series:Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
Subjects:
chalcones
isothiocyanatopropenones
thioureas
antileukemia activity
Online Access:http://www.cjm.asm.md/sites/default/files/article_files/Chemistry%20nr%202%202014%20p%2067-73.pdf

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http://www.cjm.asm.md/sites/default/files/article_files/Chemistry%20nr%202%202014%20p%2067-73.pdf

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