Functional amyloidogenesis and cytotoxicity-insights into biology and pathology.
Prions are self-templating protein structures that can be transferred from organism to organism. The [Het-s] prion propagates as a functional amyloid aggregate in the filamentous fungi Podospora anserina, and is involved in mediating heterokaryon incompatibility. Fusion of a P. anserina strain harbo...
Main Authors: | Douglas M Fowler, Jeffery W Kelly |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC3531510?pdf=render |
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