Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity

Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity

A prospective double-blind trial was conducted in Crohn's disease subjects in whom a resection was being performed, to assess the hypothesis that marginal disease would adversely influence healing of the anastomosis. Of 106 eligible patients. 51 completed a protocol of pathological assessment o...

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Main Authors: J. Wong, R.M. Preshaw, D.F. Reid, J.K. Kelly
Format: Article
Language:English
Published: Hindawi Limited 1989-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1989/458968
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spelling doaj-dfff5382889049058e85a8652662f7982020-11-24T23:29:55ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79001989-01-0133959710.1155/1989/458968Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic IntegrityJ. Wong0R.M. Preshaw1D.F. Reid2J.K. Kelly3Departments of Surgery and Pathology, University of Calgary Medical School, Calgary, Alberta, CanadaDepartments of Surgery and Pathology, University of Calgary Medical School, Calgary, Alberta, CanadaDepartments of Surgery and Pathology, University of Calgary Medical School, Calgary, Alberta, CanadaDepartments of Surgery and Pathology, University of Calgary Medical School, Calgary, Alberta, CanadaA prospective double-blind trial was conducted in Crohn's disease subjects in whom a resection was being performed, to assess the hypothesis that marginal disease would adversely influence healing of the anastomosis. Of 106 eligible patients. 51 completed a protocol of pathological assessment of the surgical specimen and a water soluble contrast enema 10 to 15 days after the surgical procedure. Six were found to have radiological leaks and three additional subjects had clinical leaks from the anastomosis. The proportion of leaks, both clinical and radiological, was nine of 54. There was no trend to increasing rate of anastomotic breakdown with increasing marginal disease.http://dx.doi.org/10.1155/1989/458968
collection DOAJ
language English
format Article
sources DOAJ
author J. Wong
R.M. Preshaw
D.F. Reid
J.K. Kelly
spellingShingle J. Wong
R.M. Preshaw
D.F. Reid
J.K. Kelly
Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity
Canadian Journal of Gastroenterology
author_facet J. Wong
R.M. Preshaw
D.F. Reid
J.K. Kelly
author_sort J. Wong
title Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity
title_short Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity
title_full Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity
title_fullStr Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity
title_full_unstemmed Resection Margin Involvement with Crohn's Disease and Postoperative Anastomotic Integrity
title_sort resection margin involvement with crohn's disease and postoperative anastomotic integrity
publisher Hindawi Limited
series Canadian Journal of Gastroenterology
issn 0835-7900
publishDate 1989-01-01
description A prospective double-blind trial was conducted in Crohn's disease subjects in whom a resection was being performed, to assess the hypothesis that marginal disease would adversely influence healing of the anastomosis. Of 106 eligible patients. 51 completed a protocol of pathological assessment of the surgical specimen and a water soluble contrast enema 10 to 15 days after the surgical procedure. Six were found to have radiological leaks and three additional subjects had clinical leaks from the anastomosis. The proportion of leaks, both clinical and radiological, was nine of 54. There was no trend to increasing rate of anastomotic breakdown with increasing marginal disease.
url http://dx.doi.org/10.1155/1989/458968
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AT dfreid resectionmargininvolvementwithcrohnsdiseaseandpostoperativeanastomoticintegrity
AT jkkelly resectionmargininvolvementwithcrohnsdiseaseandpostoperativeanastomoticintegrity
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