Identification of the Primary Factors Determining theSpecificity of Human VKORC1 Recognition by Thioredoxin-Fold Proteins

Identification of the Primary Factors Determining theSpecificity of Human VKORC1 Recognition by Thioredoxin-Fold Proteins

Redox (reduction–oxidation) reactions control many important biological processes in all organisms, both prokaryotes and eukaryotes. This reaction is usually accomplished by canonical disulphide-based pathways involving a donor enzyme that reduces the oxidised cysteine residues of a target protein,...

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Bibliographic Details
Main Authors: Maxim Stolyarchuk, Julie Ledoux, Elodie Maignant, Alain Trouvé, Luba Tchertanov
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
hVKORC1
Trx-fold proteins
protein folding
dynamics
molecular recognition
thiol–disulphide exchange
Online Access:https://www.mdpi.com/1422-0067/22/2/802

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