A Novel Dietary Intervention Reduces Circulatory Branched-Chain Amino Acids by 50%: A Pilot Study of Relevance for Obesity and Diabetes

A Novel Dietary Intervention Reduces Circulatory Branched-Chain Amino Acids by 50%: A Pilot Study of Relevance for Obesity and Diabetes

Elevated circulating branched-chain amino acids (BCAAs; isoleucine, leucine, and valine) are associated with obesity and type 2 diabetes (T2D). Reducing circulatory BCAAs by dietary restriction was suggested to mitigate these risks in rodent models, but this is a challenging paradigm to deliver in h...

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Bibliographic Details
Main Authors: Imran Ramzan, Moira Taylor, Beth Phillips, Daniel Wilkinson, Kenneth Smith, Kate Hession, Iskandar Idris, Philip Atherton
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Nutrients
Subjects:
branched-chain amino acid
essential amino acids
non-essential amino acids
restriction
dietary
maple syrup urine disease
Online Access:https://www.mdpi.com/2072-6643/13/1/95

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