Alda-1 Attenuates Hyperoxia-Induced Acute Lung Injury in Mice

Alda-1 Attenuates Hyperoxia-Induced Acute Lung Injury in Mice

Acute lung injury (ALI), a milder form of acute respiratory distress syndrome (ARDS), is a leading cause of mortality in older adults with an increasing prevalence. Oxygen therapy, is a common treatment for ALI, involving exposure to a high concentration of oxygen. Unfortunately, hyperoxia induces t...

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Bibliographic Details
Main Authors: Sahebgowda Sidramagowda Patil, Helena Hernández-Cuervo, Jutaro Fukumoto, Sudarshan Krishnamurthy, Muling Lin, Matthew Alleyn, Mason Breitzig, Venkata Ramireddy Narala, Ramani Soundararajan, Richard F. Lockey, Narasaiah Kolliputi, Lakshmi Galam
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Oxidative Stress
Hyperoxia
acute lung injury
Alda-1
aldehyde dehydrogenase 2
HALI
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.597942/full

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