Ex vivo recovery and activation of dysfunctional, anergic, monocyte-derived dendritic cells from patients with operable breast cancer: critical role of IFN-alpha

Ex vivo recovery and activation of dysfunctional, anergic, monocyte-derived dendritic cells from patients with operable breast cancer: critical role of IFN-alpha

<p>Abstract</p> <p>Background</p> <p>Dendritic cells (DCs) play a crucial role in initiating effective cell-mediated immune responses, but are dysfunctional and anergic in breast cancer. Reversal of this dysfunction and establishment of optimal DC function is a key prer...

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Main Authors: El-Sheemy Mohamad, Mckechnie Alasdair J, Chuthapisith Suebwong, Verma Chandan, Robins Richard A, Aloysius Mark M, Satthaporn Sukchai, Vassanasiri Wichai, Valerio David, Clark David, Jibril Jibril A, Eremin Oleg
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/32

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