Microbial Unmasking of Plant Glycosides

Microbial Unmasking of Plant Glycosides

The therapeutic potential of plants is widely recognized and harnessed in plant-based remedies and drug discovery. However, the factors that modulate the bioavailability and bioactivities of plant-derived phytochemicals are poorly understood. In a recent article in mBio, M. C. Theilmann et al. (mBio...

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Main Authors: Kristen A. Biernat, Bo Li, Matthew R. Redinbo
Format: Article
Language:English
Published: American Society for Microbiology 2018-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02433-17
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spelling doaj-dfd28f7de02340b783f68c093a486b4b2021-07-02T09:22:45ZengAmerican Society for MicrobiologymBio2150-75112018-01-0191e02433-1710.1128/mBio.02433-17Microbial Unmasking of Plant GlycosidesKristen A. BiernatBo LiMatthew R. RedinboThe therapeutic potential of plants is widely recognized and harnessed in plant-based remedies and drug discovery. However, the factors that modulate the bioavailability and bioactivities of plant-derived phytochemicals are poorly understood. In a recent article in mBio, M. C. Theilmann et al. (mBio 8:e01421-17, 2017, https://doi.org/10.1128/mBio.01421-17) describe how one gut microbe, Lactobacillus acidophilus, catalytically unwraps plant glucosides to make deglucosylated bioactive aglycones available to human tissues. They demonstrate that understanding the metabolism of plant glycosides by intestinal bacteria is essential to appreciating how bacteria manipulate the levels of bioactive plant metabolites in the human host.http://mbio.asm.org/cgi/content/full/9/1/e02433-17
collection DOAJ
language English
format Article
sources DOAJ
author Kristen A. Biernat
Bo Li
Matthew R. Redinbo
spellingShingle Kristen A. Biernat
Bo Li
Matthew R. Redinbo
Microbial Unmasking of Plant Glycosides
mBio
author_facet Kristen A. Biernat
Bo Li
Matthew R. Redinbo
author_sort Kristen A. Biernat
title Microbial Unmasking of Plant Glycosides
title_short Microbial Unmasking of Plant Glycosides
title_full Microbial Unmasking of Plant Glycosides
title_fullStr Microbial Unmasking of Plant Glycosides
title_full_unstemmed Microbial Unmasking of Plant Glycosides
title_sort microbial unmasking of plant glycosides
publisher American Society for Microbiology
series mBio
issn 2150-7511
publishDate 2018-01-01
description The therapeutic potential of plants is widely recognized and harnessed in plant-based remedies and drug discovery. However, the factors that modulate the bioavailability and bioactivities of plant-derived phytochemicals are poorly understood. In a recent article in mBio, M. C. Theilmann et al. (mBio 8:e01421-17, 2017, https://doi.org/10.1128/mBio.01421-17) describe how one gut microbe, Lactobacillus acidophilus, catalytically unwraps plant glucosides to make deglucosylated bioactive aglycones available to human tissues. They demonstrate that understanding the metabolism of plant glycosides by intestinal bacteria is essential to appreciating how bacteria manipulate the levels of bioactive plant metabolites in the human host.
url http://mbio.asm.org/cgi/content/full/9/1/e02433-17
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AT boli microbialunmaskingofplantglycosides
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