A prospective, randomized, controlled trial of high and low doses of Magnesium Sulfate for acute Tocolysis

At present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. Although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but it’s optimal use has yet to be delineated. In this study a high-dose protocol for m...

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Bibliographic Details
Main Authors: Behrad V, Moossavifar N, Mojtahedzadeh M, Esmaili H, Moghtadeii P
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2003-06-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/2648
Description
Summary:At present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. Although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but it’s optimal use has yet to be delineated. In this study a high-dose protocol for magnesium sulfate tocolytic therapy was compared with a low-dose regimen. One hundred patients admitted to labor unit of Imam Reza's Hospital with preterm labor were enrolled in the trial. The median times to successful tocolysis were 8 hours in the low-dose group and 4 hours in the high-dose group (P
ISSN:0044-6025
1735-9694