c-Myc is required for maintenance of glioma cancer stem cells.

c-Myc is required for maintenance of glioma cancer stem cells.

Malignant gliomas rank among the most lethal cancers. Gliomas display a striking cellular heterogeneity with a hierarchy of differentiation states. Recent studies support the existence of cancer stem cells in gliomas that are functionally defined by their capacity for extensive self-renewal and form...

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Bibliographic Details
Main Authors: Jialiang Wang, Hui Wang, Zhizhong Li, Qiulian Wu, Justin D Lathia, Roger E McLendon, Anita B Hjelmeland, Jeremy N Rich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2582454?pdf=render

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