DNA secondary structure is influenced by genetic variation and alters susceptibility to <it>de novo </it>translocation

DNA secondary structure is influenced by genetic variation and alters susceptibility to <it>de novo </it>translocation

<p>Abstract</p> <p><b>Background</b></p> <p>Cumulative evidence suggests that DNA secondary structures impact DNA replication, transcription and genomic rearrangements. One of the best studied examples is the recurrent constitutional t(11;22) in humans that...

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Bibliographic Details
Main Authors: Tsutsumi Makiko, Yamada Kouji, Ohye Tamae, Kogo Hiroshi, Tong Maoqing, Inagaki Hidehito, Kato Takema, Emanuel Beverly S, Kurahashi Hiroki
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Molecular Cytogenetics
Subjects:
Polymorphism
Palindrome
Secondary structure
Hairpin structure
Cruciform structure
Breakpoint
Translocation
Online Access:http://www.molecularcytogenetics.org/content/4/1/18

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