Systematic functional characterization of cytochrome P450 2E1 promoter variants in the Chinese Han population.

Systematic functional characterization of cytochrome P450 2E1 promoter variants in the Chinese Han population.

CYP2E1 promoter polymorphisms can lead to significant interindividual differences in expression of CYP2E1. Using a database of CYP2E1 gene polymorphisms established in 2010, our study aimed to functionally characterize the single nucleotide polymorphisms (SNPs) of the promoter region and correspondi...

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Bibliographic Details
Main Authors: Xunyi Huang, Lili Chen, Wenlong Song, Ling Chen, Jiamin Niu, Xia Han, Guoyin Feng, Lin He, Shengying Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398937?pdf=render

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