Protection by Nitric Oxide Donors of Isolated Rat Hearts Is Associated with Activation of Redox Metabolism and Ferritin Accumulation.
Preconditioning (PC) procedures (ischemic or pharmacological) are powerful procedures used for attaining protection against prolonged ischemia and reperfusion (I/R) injury, in a variety of organs, including the heart. The detailed molecular mechanisms underlying the protection by PC are however, com...
Main Authors: | Hilbert Grievink, Galina Zeltcer, Benjamin Drenger, Eduard Berenshtein, Mordechai Chevion |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4957751?pdf=render |
Similar Items
-
Sevoflurane postconditioning is not mediated by ferritin accumulation and cannot be rescued by simvastatin in isolated streptozotocin-induced diabetic rat hearts.
by: Hilbert Grievink, et al.
Published: (2019-01-01) -
The bitter fate of the sweet heart: impairment of iron homeostasis in diabetic heart leads to failure in myocardial protection by preconditioning.
by: Vladimir Vinokur, et al.
Published: (2013-01-01) -
The Loss of Myocardial Benefit following Ischemic Preconditioning Is Associated with Dysregulation of Iron Homeostasis in Diet-Induced Diabetes.
by: Vladimir Vinokur, et al.
Published: (2016-01-01) -
Cardiac protection by preconditioning is generated via an iron-signal created by proteasomal degradation of iron proteins.
by: Baruch E Bulvik, et al.
Published: (2012-01-01) -
Degeneration modulates retinal response to transient exogenous oxidative injury.
by: Michal Lederman, et al.
Published: (2014-01-01)