The Action of JAK/STAT3 and BMP/HJV/SMAD Signaling Pathways on Hepcidin Suppression by Tucum-do-Cerrado in a Normal and Iron-Enriched Diets

The Action of JAK/STAT3 and BMP/HJV/SMAD Signaling Pathways on Hepcidin Suppression by Tucum-do-Cerrado in a Normal and Iron-Enriched Diets

The Brazilian savanna fruit, tucum-do-cerrado (<i>Bactris</i><i> </i><i>setosa</i> Mart.) reduces hepatic hepcidin levels. Therefore, we investigated the effect of tucum-do-cerrado on the TfR/HFE and/or BMP/HJV/SMAD and JAK/STAT pathways, in normal and excess iron...

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Bibliographic Details
Main Authors: Sandra Fernandes Arruda, Larissa Valadares Ramos, Júlia Lima de Alencar Barbosa, Natália Aboudib Campos Hankins, Pedro Augusto Matos Rodrigues, Marcela de Sá Barreto da Cunha
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Nutrients
Subjects:
tucum-do-cerrado
hepcidin
pSMAD1/5/8
pSTAT3
iron
Online Access:https://www.mdpi.com/2072-6643/12/5/1515

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