Bone Marrow Aspirate Concentrate Harvesting and Processing Technique

Bone marrow obtained by iliac crest aspiration is a common source for harvesting mesenchymal stem cells, other progenitor cells, and associated cytokine/growth factors. Recent studies have reported good to excellent outcomes with the use of bone marrow aspirate concentrate (BMAC) for pain relief in...

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Bibliographic Details
Main Authors: Jorge Chahla, M.D., Sandeep Mannava, M.D., Ph.D., Mark E. Cinque, B.S., Andrew G. Geeslin, M.D., David Codina, M.D., Robert F. LaPrade, M.D., Ph.D.
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Arthroscopy Techniques
Online Access:http://www.sciencedirect.com/science/article/pii/S2212628716302067
Description
Summary:Bone marrow obtained by iliac crest aspiration is a common source for harvesting mesenchymal stem cells, other progenitor cells, and associated cytokine/growth factors. Recent studies have reported good to excellent outcomes with the use of bone marrow aspirate concentrate (BMAC) for pain relief in the treatment of focal chondral lesions and osteoarthritis of the knee. However, the harvesting and processing technique are crucial to achieve satisfactory results. Several studies have examined outcomes after BMAC injection, with encouraging results, but there is a lack of consensus in terms of the frequency of injection, the amount of BMAC that is injected, and the timing of BMAC injections. The purpose of this Technical Note was to describe a standardized bone marrow aspiration harvesting technique and processing method.
ISSN:2212-6287