Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys

<p>Abstract</p> <p>Background</p> <p>Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels. To further investigate this questi...

Full description

Bibliographic Details
Main Authors: MacIver M Bruce, Winegar Bruce D
Format: Article
Language:English
Published: BMC 2006-01-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/7/5