Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.

A fundamental question in G protein coupled receptor biology is how a single ligand acting at a specific receptor is able to induce a range of signaling that results in a variety of physiological responses. We focused on Type 1 cannabinoid receptor (CB₁R) as a model GPCR involved in a variety of pro...

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Bibliographic Details
Main Authors: Raphael Rozenfeld, Ittai Bushlin, Ivone Gomes, Nikos Tzavaras, Achla Gupta, Susana Neves, Lorenzo Battini, G Luca Gusella, Alexander Lachmann, Avi Ma'ayan, Robert D Blitzer, Lakshmi A Devi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3250422?pdf=render