Rutaecarpine inhibited imiquimod-induced psoriasis-like dermatitis via inhibiting the NF-κB and TLR7 pathways in mice

Rutaecarpine inhibited imiquimod-induced psoriasis-like dermatitis via inhibiting the NF-κB and TLR7 pathways in mice

Psoriasis is a chronic, immune-mediated inflammatory skin disease. As psoriasis rarely occurs in nonhuman animals, the lack of an ideal animal model reflecting the histopathological and molecular immunological characteristics of psoriasis remains an urgent issue. In the present study, an imiquimod-i...

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Bibliographic Details
Main Authors: Yongjian Li, Guiying Zhang, Mingliang Chen, Min Tong, Ming Zhao, Fang Tang, Rong Xiao, Haiquan Wen
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Psoriasis-like dermatitis
Rutaecarpine
Cytokines
NF-κB signaling
TLR7 signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221833823X

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