Loss of PGRMC1 Delays the Progression of Hepatocellular Carcinoma via Suppression of Pro-Inflammatory Immune Responses

Loss of PGRMC1 Delays the Progression of Hepatocellular Carcinoma via Suppression of Pro-Inflammatory Immune Responses

Pgrmc1 is a non-canonical progesterone receptor related to the lethality of various types of cancer. PGRMC1 has been reported to exist in co-precipitated protein complexes with epidermal growth factor receptor (EGFR), which is considered a useful therapeutic target in hepatocellular carcinoma (HCC)....

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Bibliographic Details
Main Authors: Sang R. Lee, Jong Geol Lee, Jun H. Heo, Seong Lae Jo, Jihoon Ryu, Globinna Kim, Jung-Min Yon, Myeong Sup Lee, Geun-Shik Lee, Beum-Soo An, Hyun-Jin Shin, Dong-Cheol Woo, In-Jeoung Baek, Eui-Ju Hong
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
<i>Pgrmc1</i>
liver cancer
HCC
EGFR
inflammation
Online Access:https://www.mdpi.com/2072-6694/13/10/2438

Internet

https://www.mdpi.com/2072-6694/13/10/2438

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