Increased MANF Expression in the Inferior Temporal Gyrus in Patients With Alzheimer Disease

Increased MANF Expression in the Inferior Temporal Gyrus in Patients With Alzheimer Disease

Alzheimer disease (AD) is an aging-related disorder linked to endoplasmic reticulum (ER) stress. The main pathologic feature of AD is the presence of extracellular senile plaques and intraneuronal neurofibrillary tangles (NFTs) in the brain. In neurodegenerative diseases, the unfolded protein respon...

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Bibliographic Details
Main Authors: Xue-Chun Liu, Xiu-Hong Qi, Hui Fang, Ke-Qing Zhou, Qing-Song Wang, Gui-Hai Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer disease
cerebral cortex
endoplasmic reticulum stress
MANF
hyperphosphorylated tau
senile plaque
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.639318/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.639318/full

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