Characterization of AQPs in mouse, rat and human colon and their selective regulation by bile acids

Characterization of AQPs in mouse, rat and human colon and their selective regulation by bile acids

In normal individuals, the epithelium of the colon absorbs 1.5-2 L of water a day to generate dehydrated feces. However, in the condition of bile acid malabsorption (BAM), an excess of bile acids in the colon results in diarrhea. Several studies have attempted to address the mechanisms contributing...

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Bibliographic Details
Main Authors: Jonathan Yde, Stephen Keely, Qi Wu, Johan Fredrik Borg, Natalia Lajczak, Aoife O’Dwyer, Peter Dalsgaard, Robert A Fenton, Hanne Bjerregaard Moeller
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Nutrition
Subjects:
Aquaporins
water transport
bile acid malabsorption
colonic epithelium
and bile acid diarrhea
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnut.2016.00046/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnut.2016.00046/full

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