Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics

Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics

Abstract Background Protein kinase C ζ (PKCζ), an isoform of the atypical protein kinase C, is a pivotal regulator in cancer. However, the molecular and cellular mechanisms whereby PKCζ regulates tumorigenesis and metastasis are still not fully understood. In this study, proteomics and bioinformatic...

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Bibliographic Details
Main Authors: Chunyu Hou, Yuan Li, Huiqin Liu, Mengjiao Dang, Guoxuan Qin, Ning Zhang, Ruibing Chen
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Proteome Science
Subjects:
Cancer
PKCζ; LC-MS/MS
Proteomics
Bioinformatics
Protein-protein interaction
Online Access:http://link.springer.com/article/10.1186/s12953-018-0134-8

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