Pancreatic β-Cell Senescence: Mechanisms and Association with Diabetes

Senescence occurs as a part of the cellular response to different stressors. With increasing age, continuous exposure to stressors leads to age-induced senescence. Pancreatic β-cell proliferation and glucose homeostasis also decrease with age, which results in a decrease in β cell mass and, eventual...

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Bibliographic Details
Main Authors: Sara M. Ahmed, Shimaa E. Elshenawy, Sara Sedky, Ahmed O. Elmehrath, Nagwa El-Badri
Format: Article
Language:English
Published: European Medical Journal 2021-03-01
Series:European Medical Journal
Subjects:
Online Access:https://www.emjreviews.com/diabetes/article/pancreatic-%ce%b2-cell-senescence-mechanisms-and-association-with-diabetes/