Intermembrane transfer of squalene promoted by supernatant protein factor

Supernatant protein factor (SPF), a protein that stimulates squalene epoxidation, mediates the transfer of squalene between two separable microsomal populations (Kojima, Y., E. J. Friedlander, and K. Bloch, 1981. J. Biol Chem. 256: 7235-7239). We now show that SPF also promotes the transfer of squal...

Full description

Bibliographic Details
Main Authors:	D Fuks-Holmberg, K Bloch
Format:	Article
Language:	English
Published:	Elsevier 1983-04-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520379803

id	doaj-df805e2c66174d3ea0bb0cae6e491e2b
record_format	Article
spelling	doaj-df805e2c66174d3ea0bb0cae6e491e2b2021-04-25T04:17:40ZengElsevierJournal of Lipid Research0022-22751983-04-01244402408Intermembrane transfer of squalene promoted by supernatant protein factorD Fuks-HolmbergK BlochSupernatant protein factor (SPF), a protein that stimulates squalene epoxidation, mediates the transfer of squalene between two separable microsomal populations (Kojima, Y., E. J. Friedlander, and K. Bloch, 1981. J. Biol Chem. 256: 7235-7239). We now show that SPF also promotes the transfer of squalene associated with mitochondria or with plasma membranes to total microsomes or rough or smooth microsomal subfractions. Both rough and smooth microsomes have squalene epoxidase activity that is stimulated by SPF.http://www.sciencedirect.com/science/article/pii/S0022227520379803
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	D Fuks-Holmberg K Bloch
spellingShingle	D Fuks-Holmberg K Bloch Intermembrane transfer of squalene promoted by supernatant protein factor Journal of Lipid Research
author_facet	D Fuks-Holmberg K Bloch
author_sort	D Fuks-Holmberg
title	Intermembrane transfer of squalene promoted by supernatant protein factor
title_short	Intermembrane transfer of squalene promoted by supernatant protein factor
title_full	Intermembrane transfer of squalene promoted by supernatant protein factor
title_fullStr	Intermembrane transfer of squalene promoted by supernatant protein factor
title_full_unstemmed	Intermembrane transfer of squalene promoted by supernatant protein factor
title_sort	intermembrane transfer of squalene promoted by supernatant protein factor
publisher	Elsevier
series	Journal of Lipid Research
issn	0022-2275
publishDate	1983-04-01
description	Supernatant protein factor (SPF), a protein that stimulates squalene epoxidation, mediates the transfer of squalene between two separable microsomal populations (Kojima, Y., E. J. Friedlander, and K. Bloch, 1981. J. Biol Chem. 256: 7235-7239). We now show that SPF also promotes the transfer of squalene associated with mitochondria or with plasma membranes to total microsomes or rough or smooth microsomal subfractions. Both rough and smooth microsomes have squalene epoxidase activity that is stimulated by SPF.
url	http://www.sciencedirect.com/science/article/pii/S0022227520379803
work_keys_str_mv	AT dfuksholmberg intermembranetransferofsqualenepromotedbysupernatantproteinfactor AT kbloch intermembranetransferofsqualenepromotedbysupernatantproteinfactor
_version_	1721510595208937472

Intermembrane transfer of squalene promoted by supernatant protein factor

Similar Items