The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

Abstract Introduction Adults with Down syndrome (DS) are at exceptionally high risk for Alzheimer's disease (AD), with virtually all individuals developing key neuropathological features by age 40. Identifying biomarkers of AD progression in DS can provide valuable insights into pathogenesis an...

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Main Authors: Benjamin L. Handen, Ira T. Lott, Bradley T. Christian, Nicole Schupf, Sid OBryant, Mark Mapstone, Anne M. Fagan, Joseph H. Lee, Dana Tudorascu, Mei‐Cheng Wang, Elizabeth Head, William Klunk, Beau Ances, Florence Lai, Shahid Zaman, Sharon Krinsky‐McHale, Adam M. Brickman, H. Diana Rosas, Annie Cohen, Howard Andrews, Sigan Hartley, Wayne Silverman, the Alzheimer's Biomarker Consortium‐Down Syndrome (ABC‐DS)
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
ABC‐DS
Alzheimer's disease
dementia
Down syndrome
Online Access:https://doi.org/10.1002/dad2.12065

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