Mouse acetylcholinesterase enhances neurite outgrowth of rat R28 cells through interaction with laminin-1.

Mouse acetylcholinesterase enhances neurite outgrowth of rat R28 cells through interaction with laminin-1.

The enzyme acetylcholinesterase (AChE) terminates synaptic transmission at cholinergic synapses by hydrolyzing the neurotransmitter acetylcholine, but can also exert 'non-classical', morpho-regulatory effects on developing neurons such as stimulation of neurite outgrowth. Here, we investig...

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Bibliographic Details
Main Authors: Laura E Sperling, Janine Klaczinski, Corina Schütz, Lydia Rudolph, Paul G Layer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3343015?pdf=render

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