A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine

In this article, we report a simple, effective, sensitive, non-toxic and environmentally friendly method for the detection of dopamine (DA). This method utilises the property of the self-polymerization of dopamine under alkaline conditions, and gets the concentration of dopamine by measuring the flu...

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Main Authors:	Xinghui Gong, Tong Wang, Zhendong Zhang, Xiao Wei
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-01-01
Series:	Journal of Experimental Nanoscience
Subjects:	dopamine polydopamine nahco3; fluorescence detection
Online Access:	http://dx.doi.org/10.1080/17458080.2020.1757657

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spelling	doaj-df78b5d97e5544b083ec2befcfda1b9e2020-12-17T14:55:54ZengTaylor & Francis GroupJournal of Experimental Nanoscience1745-80801745-80992020-01-0115123324110.1080/17458080.2020.17576571757657A novel and non-toxic dopamine detection method based on self-polymerisation of dopamineXinghui Gong0Tong Wang1Zhendong Zhang2Xiao Wei3Key Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region, Ministry of Education, Chang’an UniversityKey Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region, Ministry of Education, Chang’an UniversityKey Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region, Ministry of Education, Chang’an UniversityKey Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region, Ministry of Education, Chang’an UniversityIn this article, we report a simple, effective, sensitive, non-toxic and environmentally friendly method for the detection of dopamine (DA). This method utilises the property of the self-polymerization of dopamine under alkaline conditions, and gets the concentration of dopamine by measuring the fluorescence intensity of polydopamine (PDA) nanoparticles. And this method only uses NaHCO3 to start the polymerization process, so that the detection experiment becomes simple and inexpensive. The fluorescence intensities of the mixed solution produced at different reaction times and different concentrations were studied. Finally, a good linear relationship was obtained in the range of 1.0-400 μM with a correlation coefficient of 0.9946 and a detection limit of 0.3 μM. The method has high selectivity and important application value for detecting dopamine-related diseases.http://dx.doi.org/10.1080/17458080.2020.1757657dopaminepolydopaminenahco3; fluorescence detection
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Xinghui Gong Tong Wang Zhendong Zhang Xiao Wei
spellingShingle	Xinghui Gong Tong Wang Zhendong Zhang Xiao Wei A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine Journal of Experimental Nanoscience dopamine polydopamine nahco3; fluorescence detection
author_facet	Xinghui Gong Tong Wang Zhendong Zhang Xiao Wei
author_sort	Xinghui Gong
title	A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine
title_short	A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine
title_full	A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine
title_fullStr	A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine
title_full_unstemmed	A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine
title_sort	novel and non-toxic dopamine detection method based on self-polymerisation of dopamine
publisher	Taylor & Francis Group
series	Journal of Experimental Nanoscience
issn	1745-8080 1745-8099
publishDate	2020-01-01
description	In this article, we report a simple, effective, sensitive, non-toxic and environmentally friendly method for the detection of dopamine (DA). This method utilises the property of the self-polymerization of dopamine under alkaline conditions, and gets the concentration of dopamine by measuring the fluorescence intensity of polydopamine (PDA) nanoparticles. And this method only uses NaHCO3 to start the polymerization process, so that the detection experiment becomes simple and inexpensive. The fluorescence intensities of the mixed solution produced at different reaction times and different concentrations were studied. Finally, a good linear relationship was obtained in the range of 1.0-400 μM with a correlation coefficient of 0.9946 and a detection limit of 0.3 μM. The method has high selectivity and important application value for detecting dopamine-related diseases.
topic	dopamine polydopamine nahco3; fluorescence detection
url	http://dx.doi.org/10.1080/17458080.2020.1757657
work_keys_str_mv	AT xinghuigong anovelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine AT tongwang anovelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine AT zhendongzhang anovelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine AT xiaowei anovelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine AT xinghuigong novelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine AT tongwang novelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine AT zhendongzhang novelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine AT xiaowei novelandnontoxicdopaminedetectionmethodbasedonselfpolymerisationofdopamine
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A novel and non-toxic dopamine detection method based on self-polymerisation of dopamine

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