Dietary Fat-Accelerating Leptin Signaling Promotes Protumorigenic Gastric Environment in Mice

Dietary Fat-Accelerating Leptin Signaling Promotes Protumorigenic Gastric Environment in Mice

Excess of fat intake leads to obesity and causes a variety of metabolic diseases and cancer. We previously demonstrated that high-lard diet induces intestinal metaplasia, a precancerous lesion of the stomach mediated by leptin signaling. This study aims to investigate which kinds of dietary fat caus...

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Bibliographic Details
Main Authors: Seiya Arita, Takumi Ogawa, Yuta Murakami, Yuta Kinoshita, Masaharu Okazaki, Kyoko Inagaki-Ohara
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Nutrients
Subjects:
high-fat
leptin
stomach
microbiota
protumorigenesis
Online Access:https://www.mdpi.com/2072-6643/11/9/2127

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