Estimating the evidence of selection and the reliability of inference in unigenic evolution

Estimating the evidence of selection and the reliability of inference in unigenic evolution

<p>Abstract</p> <p>Background</p> <p>Unigenic evolution is a large-scale mutagenesis experiment used to identify residues that are potentially important for protein function. Both currently-used methods for the analysis of unigenic evolution data analyze 'windows&#...

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Bibliographic Details
Main Authors: Edgell David R, Kleinstiver Benjamin P, Fernandes Andrew D, Wahl Lindi M, Gloor Gregory B
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Algorithms for Molecular Biology
Online Access:http://www.almob.org/content/5/1/35

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