Generation by reverse genetics of an effective, stable, live-attenuated newcastle disease virus vaccine based on a currently circulating, highly virulent Indonesian strain.

Newcastle disease virus (NDV) can cause severe disease in chickens. Although NDV vaccines exist, there are frequent reports of outbreaks in vaccinated chickens. During 2009-2010, despite intense vaccination, NDV caused major outbreaks among commercial poultry farms in Indonesia. These outbreaks rais...

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Bibliographic Details
Main Authors: Sa Xiao, Baibaswata Nayak, Arthur Samuel, Anandan Paldurai, Mallikarjuna Kanabagattebasavarajappa, Teguh Y Prajitno, Eny E Bharoto, Peter L Collins, Siba K Samal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528709?pdf=render