Traditional and Recent Evidence on Five Phytopharmaceuticals from Rosa damascena Herrm.

• Main Authors: Forough Afsari Sardari, Ghazaleh Mosleh, Amir Azadi, Abdolali Mohagheghzadeh, Parmis Badr*
• Format: Article
• Language: English
• Published: Iranian Society of Pharmacognosy 2019-07-01
• Series: Research Journal of Pharmacognosy
• Subjects: Rosa damascena; Iranian traditional medicine; phytopharmaceutical
• Online Access: http://www.rjpharmacognosy.ir/article_89469_5e50d839d88760b22836f8bd98191ad5.pdf

Damask rose or <em>Rosa damascena </em>Herrm. is one of the most widely-used medicinal herbs in Iranian Traditional Medicine (ITM). Because of different types of phytochemicals such as flavonoids, glycosides, terpenes, and anthocyanins,<em> R.</em> <em>damascena </em>flowers have a wide range of pharmacological effects. Five traditional <em>Rosa</em> phytopharmaceuticals are “Golangebin”/ “Golqand<em>”</em> (the mixture of petals in honey/sugar), “Jollab”, rose oil, rose water, and rose syrup. In the current study, traditional information about these phytopharmaceuticals was extracted from three medieval manuscripts including “Al-Shamil fi al-Tibb” (13^th century AD), “Qarabadin Salehi” (1766), and “Qarabadin Kabir” (1780). Articles on <em>R. damascena</em> petal were found by searching Pubmed, Scopus, and Google Scholar till June 2018. They were mainly related to effectiveness on CNS and GI systems. Numerous studies have been performed to evaluate the efficacy and safety of <em>R. damascena</em> extracts and essential oil, but little has been focused on these phytopharmaceuticals as complementary therapies for the mentioned effects. Comparing recent findings and traditional knowledge of these <em>R. damascena</em> phytopharmaceuticals shows a wide gap between these two viewpoints. Therefore, numerous opportunities are provided to evaluate traditional therapeutic notions about <em>R. damascena</em> phytopharmaceuticals leading to increase for their chances of application.