Ureaplasma diversum and Its Membrane-Associated Lipoproteins Activate Inflammatory Genes Through the NF-κB Pathway via Toll-Like Receptor 4

Ureaplasma diversum and Its Membrane-Associated Lipoproteins Activate Inflammatory Genes Through the NF-κB Pathway via Toll-Like Receptor 4

Objectives:Ureaplasma diversum is a pathogen of cows that may cause intense inflammatory responses in the reproductive tract and interfere with bovine reproduction. The aims of this study were to evaluate the immune response of bovine blastocysts and macrophages to U. diversum infection and to evalu...

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Main Authors: Manoel N. Santos-Junior, Izadora S. Rezende, Clarissa L. S. Souza, Maysa S. Barbosa, Guilherme B. Campos, Laís F. Brito, Éllunny C. Queiroz, Elaine N. Barbosa, Mariana M. Teixeira, Letícia O. Da Silva, Lucas S. C. Silva, Flávia S. Nascimento, Tassyo L. Da Silva, Adam A. Martens, Adriano F. P. Siqueira, Mayra E. O. D’Avila Assumpção, Glaucia M. Machado-Santelli, Bruno L. Bastos, Ana M. S. Guimarães, Jorge Timenetsky, Lucas M. Marques
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
Ureaplasma diversum
immunogenicity
macrophages
blastocysts
LAMPs
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01538/full

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