Effects of berberine on the secretion of cytokines and expression of genes involved in cell cycle regulation in THP-1 monocytic cell line

Objective(s): Current acute myeloid leukemia (AML) therapeutic strategies have irreversible side-effects. Berberine (BBR) is an isoquinoline alkaloid, which has been known as an aryl hydrocarbon receptor (AhR) ligand. AhR is a cytoplasmic receptor, which is involved in the regulation of cellular and...

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Bibliographic Details
Main Authors: Saeed Mohammadi, Fakhri Sadat Seyedhoseini, Jahanbakhsh Asadi, Yaghoub Yazdani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-05-01
Series:Iranian Journal of Basic Medical Sciences
Online Access:http://ijbms.mums.ac.ir/article_8677_94bbcc06a38e03d712ab56d52fb45622.pdf