PALLIA‐10, a screening tool to identify patients needing palliative care referral in comprehensive cancer centers: A prospective multicentric study (PREPA‐10)

• Main Authors: Yann Molin, Caroline Gallay, Julien Gautier, Audrey Lardy‐Cleaud, Romaine Mayet, Marie‐Christine Grach, Gérard Guesdon, Géraldine Capodano, Olivier Dubroeucq, Carole Bouleuc, Nathalie Bremaud, Anne Fogliarini, Aline Henry, Nathalie Caunes‐Hilary, Stéphanie Villet, Christine Villatte, Véronique Frasie, Valérie Triolaire, Véronique Barbarot, Jean‐Marie Commer, Agnès Hutin, Gisèle Chvetzoff
• Format: Article
• Language: English
• Published: Wiley 2019-06-01
• Series: Cancer Medicine
• Subjects: advanced cancer; decision making; palliative care; prognosis; quality of life; surveys and questionnaire
• Online Access: https://doi.org/10.1002/cam4.2118

Abstract Purpose The identification and referral of patients in need of palliative care should be improved. The French society for palliative support and care recommended to use the PALLIA‐10 questionnaire and its score greater than 3 to refer patients to palliative care. We explored the use of the PALLIA‐10 questionnaire and its related score in a population of advanced cancer patients. Methods This prospective multicentric study is to be conducted in authorized French comprehensive cancer centers on hospitalized patients on a given day. We aimed to use the PALLIA‐10 score to determine the proportion of palliative patients with a score >3. Main secondary endpoints were to determine the proportion of patients already managed by palliative care teams at the study date or referred to palliative care in six following months, the prevalence of patients with a score greater than 5, and the overall survival using the predefined thresholds of 3 and 5. Results In 2015, eighteen French cancer centers enrolled 840 patients, including 687 (82%) palliative patients. 479 (69.5%) patients had a score >3, 230 (33.5%) had a score >5, 216 (31.4%) patients were already followed‐up by a palliative care team, 152 patients were finally referred to PC in the six subsequent months. The PALLIA‐10 score appeared as a reliable predictive (adjusted ORRef≤3: 1.9 [1.17‐3.16] and 3.59 [2.18‐5.91]) and prognostic (adjusted HRRef≤3 = 1.58 [95%CI 1.20‐2.08] and 2.18 [95%CI 1.63‐2.92]) factor for patients scored 4‐5 and >5, respectively. Conclusion The PALLIA‐10 questionnaire is an easy‐to‐use tool to refer cancer inpatients to palliative care in current practice. However a score greater than 5 using the PALLIA‐10 questionnaire would be more appropriate for advanced cancer patients hospitalized in comprehensive cancer center.